Can Nasal Polyps Come Back after Surgery ? How To Cure Nasal Polyps ?


Staphylococcus aureus is a frequent colonizer of the upper airways in chronic rhinosinusitis with nasal polyps, but also resides intramucosally; it has been shown that secreted staphylococcal proteins such as enterotoxins and serine proteases induce the release of cytokines such as IL-5. 

Recent study have analyzed nasal polyp tissue freshly obtained during routine surgery, which did or did not contain cultivatable S. aureus, to study spontaneous IL-5 production by nasal polyp tissue over 24 and 72 h in tissue culture. In S. aureus-positive samples was interfered by killing the bacteria using antibiotics or S. aureus specific intravenous staphylococcal phages (ISP), active or heat-inactivated

This study also demonstrate that cultivatable S. aureus may be found in type-2 inflamed nasal polyps; the pathogen is replicating within 24 h and secretes proteins, including enterotoxins and serine proteases. The presence of S. aureus was associated with a significantly higher release of IL-5. Killing of S. aureus by antibiotics or specific ISP significantly reduced the IL-5 release. The suppressive activity of the bacteriophage on IL-5 be abolished by heat inactivation or anti-phage antibodies. That's why nasal polyps still come back after surgery.

This study also discovered bacterial proteins including enterotoxins and serine proteases like proteins. These experiments indicate a direct role of S. aureus in the regulation of IL-5 production in nasal polyps and may suggest the involvement of bacterial proteins detected in the tissues. So natural treatment can help patients get rid of nasal polyps.

Read more : Natural Way to Get rid of Nasal Polyps

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Natural Way to Treat Nasal Polyps

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Chronic rhinosinusitis with nasal polyposis (CRSwNP) frequently coexists with asthma. This analysis examined improvements inquality of life (QoL) in patients with Nasal Polyps and comorbid asthmatreated with this natural way  versus placebo. Analyses were conducted in a pre-specified subgroup ofpatients with corticosteroid-refractory Nasal Polyps and comorbid asthma enrolled in phase III, placebo-controlled, 24-week, trials of omalizumab,P OLYP1 (n574) and POLYP2 (n577). The odds of achieving minimallyimportant difference (MID;>_0.5 points) in the Asthma Quality of Life  (AQLQ) at Week 24 and mean change from baseline toWeek 24 in the sino-nasal outcome test At baseline, mean  Quality of Life scores were 4.6 (1.4) and 5.1(1.3) and mean SNOT-22 scores were 62.2 (18.0) and 61.7 (17.3) inpatients with asthma from POLYP1 and POLYP2. Omalizumab-treatedpatients were significantly more likely than placebo-treated patients toachieve MID in AQLQ in each study. In the pooled pop...
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What is Natural Way to Treat Nasal Polyps without side effects ?

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  Chronic rhinosinusitis with nasal polyps (CRSwNP) is a major health care problem that affects from 0.5% to 4% of the generalpopulation Nasalo Polyps leads to high management costs and poor quality of life of affected subjects and shows a wide diversity ofinflammatory  phenotypes.   Studies  have  demonstrated  thateosinophil infiltration and TH2-biased cytokine profiles are keyfeatures of white patients with  Nasalo Polyps whereas nasal polyps  from southern Chinese patients have been shown to becharacterized by neutrophilic inflammation and a significant increase in TH1/TH17 cell pattern. Given the inflammatory nature of Nasal Polyps, corticosteroids aretypically regarded as the mainstay of medical treatment forthis condition.Although topical intranasal steroid sprayshave  proved  to  be an effective  treatment  for  Nasal polyps and maintain a minimal risk profile,long-term administration of nasal spray is n...
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